COMPACT WASHING AND DEPYROGENATING LINE

    Steriline has developed a small footprint vial (or ampoule) rotary washing machine and depyrogenating tunnel suitable for clinical manufacturing, laboratory, and R&D applications. Based on a monoblock principal, the washing machine is fully integrated with a laminar flow depyrogenation tunnel on a single frame.

    The rotary washing machine, utilizes gripper mechanisms to handle the glassware and ensures thorough washing and the siliconization of the glassware. The glassware is loaded onto a rotating table and then automatically loaded into the grippers. The glassware passes through the washing and drying station in an upside down position. The washer is equipped with needles which are lifted to penetrate the glassware and then spray the appropriate washing fluid(s) and the compressed air.

    After washing, the glassware is up-righted and directly discharged onto the depyrogenation tunnel conveyor belt. The vials pass through the inlet chamber then enter the hot chamber, where the depyrogenating process takes place. The glassware never stops moving and then enters the cooling chamber to cool down to a suitable temperature before discharge. The conveyor belt system is divided in three parts to  increase the  efficiency of  each chamber. This system ensures a savings of energy normally lost to the heat up and cool down of the conveyor belt as it passes from chamber to chamber.

    At the end of the batch, all vials/ampoules are discharged onto the dead plate between the tunnel and the filling machine by means of a discharge bar.  The depyrogenating tunnel has the added advantage of recycling the air in all the three chambers, which allows to remove many of the traditional intake and exhaust ducts. The pressure differential between the cooling chamber and the inlet chamber traditionally allows for about 100 air changes per hour in each chamber.

    The highly accurate automatic control of air speed in the chambers and of the pressure control inside the tunnel has always been one of the greatest advantages of Steriline's depyrogenating tunnels.

    When the depyrogenating tunnel is equipped with the optional dry heat sterilizable cooling chamber, a heated airtight door is provided. This option also enables the connection of the tunnel to the downstream isolator.

    A user-friendly touch screen HMI provides a seamless interface between the operator and the PLC.

    A remarkable break though in technology, in this small footprint, this washing and depyrogenation line is fully compliant with GAMP, cGMP regulations and the latest FDA requirements. The same monoblock concept can also be applied on our full size production equipment.

Download the PDF Brochure

Compact Washing & Depyrogenation Line Brochure

Compact Washing & Depyrogenation Monoblock

Full Size Production Monoblock

Rotary Washer with Depyrogenation Tunnel, combined onto approximately a 3' x 6' single frame

SW series Syringe Washer with a ST5 Depyrogenation Tunnel

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Compact Washing & Depyrogenation Monoblock

Rotary Washer with Depyrogenation Tunnel, combined onto approximately a 3' x 6' single frame

 

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Last modified: 10/12/06